Inger Johansson Selected Research

(1- (chloromethyl)- 1,2- dihydropyrrolo(3,2- e)indol- 3(6H)- yl)(5- fluoro- 1H- indol- 2- yl)methanone

6/2013

Colon cancer-specific cytochrome P450 2W1 converts duocarmycin analogues into potent tumor cytotoxins.

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Inger Johansson Research Topics

Disease

11	Neoplasms (Cancer) 11/2022 - 03/2006
6	Colonic Neoplasms (Colon Cancer) 02/2016 - 12/2010
5	Colorectal Neoplasms (Colorectal Cancer) 01/2016 - 12/2010
3	Androgen-Insensitivity Syndrome (Testicular Feminization) 01/2021 - 10/2016
3	Hepatocellular Carcinoma (Hepatoma) 01/2020 - 04/2004
3	Infections 12/2015 - 09/2002
2	Breast Neoplasms (Breast Cancer) 01/2021 - 01/2016
2	Cardiovascular Diseases (Cardiovascular Disease) 10/2016 - 06/2008
2	Neoplasm Metastasis (Metastasis) 01/2016 - 07/2014
2	Adrenocortical Carcinoma 01/2016 - 01/2016
1	Burns 01/2021
1	Alcoholic Fatty Liver 01/2020
1	Liver Cirrhosis (Hepatic Cirrhosis) 01/2020
1	Fibrosis (Cirrhosis) 01/2020
1	Fatty Liver 01/2018
1	Atherosclerosis 01/2018
1	Liver Diseases (Liver Disease) 11/2016
1	Hyperplasia 10/2016
1	Vascular System Injuries 10/2016
1	Rhabdomyosarcoma 01/2016
1	Asymptomatic Diseases 12/2015
1	Genetic Predisposition to Disease (Genetic Predisposition) 01/2015
1	Peripheral Nervous System Diseases (PNS Diseases) 01/2015
1	Acute Disease 12/2013
1	Opportunistic Infections (Opportunistic Infection) 12/2013
1	Lyme Neuroborreliosis 09/2011
1	Neuromuscular Diseases (Neuromuscular Disease) 09/2011
1	Chemical and Drug Induced Liver Injury 05/2011
1	Drug-Related Side Effects and Adverse Reactions 03/2011
1	Hypopituitarism (Sheehan's Syndrome) 04/2009
1	Alcoholic Liver Diseases (Alcoholic Liver Disease) 03/2009
1	Necrosis 05/2008
1	Head and Neck Neoplasms (Head and Neck Cancer) 11/2005
1	Weight Loss (Weight Reduction) 11/2005
1	Cholelithiasis 09/2005

Drug/Important Bio-Agent (IBA)

10	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 01/2021 - 01/2003
10	Pharmaceutical PreparationsIBA 01/2018 - 03/2006
8	EnzymesIBA 02/2016 - 03/2006
5	ProdrugsIBA 01/2016 - 12/2010
5	DuocarmycinsIBA 01/2015 - 06/2013
3	Proteins (Proteins, Gene)FDA Link 01/2016 - 09/2011
2	AndrogensIBA 01/2021 - 10/2016
2	Transcription Factors (Transcription Factor)IBA 01/2020 - 04/2004
2	Testosterone (Sustanon)FDA Link 01/2018 - 01/2016
2	Androgen Receptors (Androgen Receptor)IBA 01/2018 - 10/2016
2	AntibodiesIBA 01/2016 - 12/2010
2	(5- chloro- 1H- indol- 2- yl)(1- (chloromethyl)- 1,2- dihydropyrrolo(3,2- e)indol- 3(6H)- yl)methanoneIBA 10/2013 - 06/2013
2	GhrelinIBA 06/2008 - 05/2008
1	Complement System Proteins (Complement)IBA 11/2022
1	LipidsIBA 01/2021
1	Cytochrome P-450 CYP2D6 (CYP2D6)IBA 01/2021
1	Tamoxifen FDA LinkGeneric 01/2021
1	Small Interfering RNA (siRNA)IBA 01/2020
1	Apolipoproteins E (ApoE)IBA 01/2018
1	Gonadal Steroid Hormones (Sex Hormones)IBA 10/2016
1	Vitamin A (Retinol)FDA LinkGeneric 01/2016
1	Dihydrotachysterol (AT 10)IBA 12/2015
1	SuspensionsIBA 01/2015
1	Paclitaxel (Taxol)FDA LinkGeneric 01/2015
1	Imatinib Mesylate (Gleevec)FDA Link 01/2015
1	Valganciclovir FDA Link 12/2013
1	Ganciclovir (Cytovene)FDA LinkGeneric 12/2013
1	Cytochrome P-450 CYP1A1 (CYP1A1)IBA 08/2013
1	cyclopropapyrroloindoleIBA 08/2013
1	(1- (chloromethyl)- 1,2- dihydropyrrolo(3,2- e)indol- 3(6H)- yl)(5- fluoro- 1H- indol- 2- yl)methanoneIBA 06/2013
1	Cytotoxins (Cytolysins)IBA 06/2013
1	Histones (Histone)IBA 06/2013
1	Mixed Function Oxygenases (Monooxygenases)IBA 06/2013
1	Biomarkers (Surrogate Marker)IBA 09/2011
1	Dystroglycans (Dystroglycan)IBA 09/2011
1	Codeine (Codeine Phosphate)FDA LinkGeneric 03/2011
1	Tramadol (K315)FDA LinkGeneric 03/2011
1	AcenocoumarolIBA 03/2011
1	Clopidogrel (Plavix)FDA Link 03/2011
1	CytochromesIBA 03/2011
1	Warfarin (Coumadin)FDA LinkGeneric 03/2011
1	Cortisone FDA Link 04/2009
1	Thyroxine (Levothyroxine)FDA LinkGeneric 04/2009
1	Cytochrome P-450 CYP2E1 (CYP2E1)IBA 03/2009
1	Reactive Oxygen Species (Oxygen Radicals)IBA 03/2009
1	Ethanol (Ethyl Alcohol)IBA 03/2009
1	Annexin A5IBA 05/2008
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 05/2008
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 05/2008
1	hexarelinIBA 05/2008
1	Caspase 3 (Caspase-3)IBA 05/2008
1	Messenger RNA (mRNA)IBA 03/2006
1	Protein Isoforms (Isoforms)IBA 03/2006
1	Bile Acids and Salts (Bile Acids)IBA 09/2005
1	Cholesterol 7-alpha-Hydroxylase (Cholesterol 7 alpha Hydroxylase)IBA 09/2005

Therapy/Procedure

5	Therapeutics 02/2016 - 03/2006
2	Castration 01/2021 - 01/2018
2	Drug Therapy (Chemotherapy) 01/2020 - 06/2013
1	Thymectomy 01/2018
1	Transplantation 12/2015
1	Drug Tapering 01/2015
1	Lung Transplantation 12/2013
1	Hypophysectomy 04/2009
1	Aftercare (After-Treatment) 11/2005
1	Radiotherapy 11/2005